diff --git a/backend/open_webui/config.py b/backend/open_webui/config.py
index 49ab1a9aad..30f740d35e 100644
--- a/backend/open_webui/config.py
+++ b/backend/open_webui/config.py
@@ -2250,6 +2250,28 @@ RAG_ALLOWED_FILE_EXTENSIONS = PersistentConfig(
     ],
 )
 
+# File decryption settings
+ENABLE_FILE_DECRYPTION = PersistentConfig(
+    "ENABLE_FILE_DECRYPTION",
+    "file_decryption.enable",
+    os.environ.get("ENABLE_FILE_DECRYPTION", "False").lower() == "true",
+)
+FILE_DECRYPTION_ENDPOINT = PersistentConfig(
+    "FILE_DECRYPTION_ENDPOINT",
+    "file_decryption.endpoint",
+    os.environ.get("FILE_DECRYPTION_ENDPOINT", ""),
+)
+FILE_DECRYPTION_API_KEY = PersistentConfig(
+    "FILE_DECRYPTION_API_KEY",
+    "file_decryption.api_key",
+    os.environ.get("FILE_DECRYPTION_API_KEY", ""),
+)
+FILE_DECRYPTION_TIMEOUT = PersistentConfig(
+    "FILE_DECRYPTION_TIMEOUT",
+    "file_decryption.timeout",
+    int(os.environ.get("FILE_DECRYPTION_TIMEOUT", "30")),
+)
+
 RAG_EMBEDDING_ENGINE = PersistentConfig(
     "RAG_EMBEDDING_ENGINE",
     "rag.embedding_engine",
diff --git a/backend/open_webui/main.py b/backend/open_webui/main.py
index 595d551d75..10f5b8e925 100644
--- a/backend/open_webui/main.py
+++ b/backend/open_webui/main.py
@@ -223,6 +223,10 @@ from open_webui.config import (
     RAG_AZURE_OPENAI_API_VERSION,
     RAG_OLLAMA_BASE_URL,
     RAG_OLLAMA_API_KEY,
+    ENABLE_FILE_DECRYPTION,
+    FILE_DECRYPTION_ENDPOINT,
+    FILE_DECRYPTION_API_KEY,
+    FILE_DECRYPTION_TIMEOUT,
     CHUNK_OVERLAP,
     CHUNK_SIZE,
     CONTENT_EXTRACTION_ENGINE,
@@ -818,6 +822,11 @@ app.state.config.RAG_AZURE_OPENAI_API_VERSION = RAG_AZURE_OPENAI_API_VERSION
 app.state.config.RAG_OLLAMA_BASE_URL = RAG_OLLAMA_BASE_URL
 app.state.config.RAG_OLLAMA_API_KEY = RAG_OLLAMA_API_KEY
 
+app.state.config.ENABLE_FILE_DECRYPTION = ENABLE_FILE_DECRYPTION
+app.state.config.FILE_DECRYPTION_ENDPOINT = FILE_DECRYPTION_ENDPOINT
+app.state.config.FILE_DECRYPTION_API_KEY = FILE_DECRYPTION_API_KEY
+app.state.config.FILE_DECRYPTION_TIMEOUT = FILE_DECRYPTION_TIMEOUT
+
 app.state.config.PDF_EXTRACT_IMAGES = PDF_EXTRACT_IMAGES
 
 app.state.config.YOUTUBE_LOADER_LANGUAGE = YOUTUBE_LOADER_LANGUAGE
@@ -1616,6 +1625,7 @@ async def get_app_config(request: Request):
                         "width": app.state.config.FILE_IMAGE_COMPRESSION_WIDTH,
                         "height": app.state.config.FILE_IMAGE_COMPRESSION_HEIGHT,
                     },
+                    "decryption_enabled": app.state.config.ENABLE_FILE_DECRYPTION,
                 },
                 "permissions": {**app.state.config.USER_PERMISSIONS},
                 "google_drive": {
diff --git a/backend/open_webui/routers/retrieval.py b/backend/open_webui/routers/retrieval.py
index fac5706f03..a8e15a6a10 100644
--- a/backend/open_webui/routers/retrieval.py
+++ b/backend/open_webui/routers/retrieval.py
@@ -397,6 +397,11 @@ async def get_rag_config(request: Request, user=Depends(get_admin_user)):
         "TOP_K_RERANKER": request.app.state.config.TOP_K_RERANKER,
         "RELEVANCE_THRESHOLD": request.app.state.config.RELEVANCE_THRESHOLD,
         "HYBRID_BM25_WEIGHT": request.app.state.config.HYBRID_BM25_WEIGHT,
+        # File decryption settings    
+        "ENABLE_FILE_DECRYPTION": request.app.state.config.ENABLE_FILE_DECRYPTION,  
+        "FILE_DECRYPTION_ENDPOINT": request.app.state.config.FILE_DECRYPTION_ENDPOINT,   
+        "FILE_DECRYPTION_API_KEY": request.app.state.config.FILE_DECRYPTION_API_KEY,  
+        "FILE_DECRYPTION_TIMEOUT": request.app.state.config.FILE_DECRYPTION_TIMEOUT,
         # Content extraction settings
         "CONTENT_EXTRACTION_ENGINE": request.app.state.config.CONTENT_EXTRACTION_ENGINE,
         "PDF_EXTRACT_IMAGES": request.app.state.config.PDF_EXTRACT_IMAGES,
@@ -611,6 +616,12 @@ class ConfigForm(BaseModel):
     ENABLE_GOOGLE_DRIVE_INTEGRATION: Optional[bool] = None
     ENABLE_ONEDRIVE_INTEGRATION: Optional[bool] = None
 
+    # File decryption settings
+    ENABLE_FILE_DECRYPTION: Optional[bool] = None
+    FILE_DECRYPTION_ENDPOINT: Optional[str] = None
+    FILE_DECRYPTION_API_KEY: Optional[str] = None
+    FILE_DECRYPTION_TIMEOUT: Optional[int] = None
+
     # Web search settings
     web: Optional[WebConfig] = None
 
@@ -889,6 +900,28 @@ async def update_rag_config(
         else request.app.state.config.ENABLE_ONEDRIVE_INTEGRATION
     )
 
+    # File decryption settings
+    request.app.state.config.ENABLE_FILE_DECRYPTION = (
+        form_data.ENABLE_FILE_DECRYPTION
+        if form_data.ENABLE_FILE_DECRYPTION is not None
+        else request.app.state.config.ENABLE_FILE_DECRYPTION
+    )
+    request.app.state.config.FILE_DECRYPTION_ENDPOINT = (
+        form_data.FILE_DECRYPTION_ENDPOINT
+        if form_data.FILE_DECRYPTION_ENDPOINT is not None
+        else request.app.state.config.FILE_DECRYPTION_ENDPOINT
+    )
+    request.app.state.config.FILE_DECRYPTION_API_KEY = (
+        form_data.FILE_DECRYPTION_API_KEY
+        if form_data.FILE_DECRYPTION_API_KEY is not None
+        else request.app.state.config.FILE_DECRYPTION_API_KEY
+    )
+    request.app.state.config.FILE_DECRYPTION_TIMEOUT = (
+        form_data.FILE_DECRYPTION_TIMEOUT
+        if form_data.FILE_DECRYPTION_TIMEOUT is not None
+        else request.app.state.config.FILE_DECRYPTION_TIMEOUT
+    )
+
     if form_data.web is not None:
         # Web search settings
         request.app.state.config.ENABLE_WEB_SEARCH = form_data.web.ENABLE_WEB_SEARCH
@@ -1045,6 +1078,11 @@ async def update_rag_config(
         # Integration settings
         "ENABLE_GOOGLE_DRIVE_INTEGRATION": request.app.state.config.ENABLE_GOOGLE_DRIVE_INTEGRATION,
         "ENABLE_ONEDRIVE_INTEGRATION": request.app.state.config.ENABLE_ONEDRIVE_INTEGRATION,
+        # File decryption settings
+        "ENABLE_FILE_DECRYPTION": request.app.state.config.ENABLE_FILE_DECRYPTION,
+        "FILE_DECRYPTION_ENDPOINT": request.app.state.config.FILE_DECRYPTION_ENDPOINT,
+        "FILE_DECRYPTION_API_KEY": request.app.state.config.FILE_DECRYPTION_API_KEY,
+        "FILE_DECRYPTION_TIMEOUT": request.app.state.config.FILE_DECRYPTION_TIMEOUT,
         # Web search settings
         "web": {
             "ENABLE_WEB_SEARCH": request.app.state.config.ENABLE_WEB_SEARCH,
diff --git a/backend/open_webui/storage/provider.py b/backend/open_webui/storage/provider.py
index 41a92fafe9..a000ec7045 100644
--- a/backend/open_webui/storage/provider.py
+++ b/backend/open_webui/storage/provider.py
@@ -26,6 +26,10 @@ from open_webui.config import (
     AZURE_STORAGE_KEY,
     STORAGE_PROVIDER,
     UPLOAD_DIR,
+    ENABLE_FILE_DECRYPTION,
+    FILE_DECRYPTION_ENDPOINT,
+    FILE_DECRYPTION_API_KEY,
+    FILE_DECRYPTION_TIMEOUT,
 )
 from google.cloud import storage
 from google.cloud.exceptions import GoogleCloudError, NotFound
@@ -35,11 +39,36 @@ from azure.storage.blob import BlobServiceClient
 from azure.core.exceptions import ResourceNotFoundError
 from open_webui.env import SRC_LOG_LEVELS
 
+from open_webui.utils.decryption import (
+    decrypt_file_via_azure,
+    DecryptionError,
+)
 
 log = logging.getLogger(__name__)
 log.setLevel(SRC_LOG_LEVELS["MAIN"])
 
 
+def _decrypt_content_if_enabled(filename: str, contents: bytes) -> bytes:
+    """Checks config and decrypts file contents if enabled."""
+
+    if ENABLE_FILE_DECRYPTION and FILE_DECRYPTION_ENDPOINT and FILE_DECRYPTION_API_KEY:
+        try:
+            decrypted_contents = decrypt_file_via_azure(
+                filename,
+                contents,
+                FILE_DECRYPTION_ENDPOINT,
+                FILE_DECRYPTION_API_KEY,
+                FILE_DECRYPTION_TIMEOUT,
+            )
+            log.info(f"File {filename} decrypted successfully.")
+            return decrypted_contents
+        except Exception as e:
+            log.error(f"File decryption failed: {e}")
+            # Raise a specific error to be caught by the API layer
+            raise DecryptionError(f"File decryption failed: {e}")
+    return contents
+
+
 class StorageProvider(ABC):
     @abstractmethod
     def get_file(self, file_path: str) -> str:
@@ -68,6 +97,10 @@ class LocalStorageProvider(StorageProvider):
         contents = file.read()
         if not contents:
             raise ValueError(ERROR_MESSAGES.EMPTY_CONTENT)
+
+        # Decrypt contents if decryption is enabled in the config
+        contents = _decrypt_content_if_enabled(filename, contents)
+
         file_path = f"{UPLOAD_DIR}/{filename}"
         with open(file_path, "wb") as f:
             f.write(contents)
diff --git a/src/lib/components/admin/Settings/Documents.svelte b/src/lib/components/admin/Settings/Documents.svelte
index 993cc6553f..e31d489e14 100644
--- a/src/lib/components/admin/Settings/Documents.svelte
+++ b/src/lib/components/admin/Settings/Documents.svelte
@@ -136,6 +136,14 @@
 	};
 
 	const submitHandler = async () => {
+		if (
+			RAGConfig.ENABLE_FILE_DECRYPTION &&
+			(!RAGConfig.FILE_DECRYPTION_ENDPOINT || !RAGConfig.FILE_DECRYPTION_API_KEY)
+		) {
+			toast.error($i18n.t('Endpoint URL and API Key are required when file decryption is enabled.'));
+			return;
+		}
+
 		if (
 			RAGConfig.CONTENT_EXTRACTION_ENGINE === 'external' &&
 			RAGConfig.EXTERNAL_DOCUMENT_LOADER_URL === ''
@@ -192,6 +200,10 @@
 
 		const res = await updateRAGConfig(localStorage.token, {
 			...RAGConfig,
+			ENABLE_FILE_DECRYPTION: RAGConfig.ENABLE_FILE_DECRYPTION ?? false,
+			FILE_DECRYPTION_ENDPOINT: RAGConfig.FILE_DECRYPTION_ENDPOINT ?? '',
+			FILE_DECRYPTION_API_KEY: RAGConfig.FILE_DECRYPTION_API_KEY ?? '',
+			FILE_DECRYPTION_TIMEOUT: RAGConfig.FILE_DECRYPTION_TIMEOUT ?? 30,
 			ALLOWED_FILE_EXTENSIONS: RAGConfig.ALLOWED_FILE_EXTENSIONS.split(',')
 				.map((ext) => ext.trim())
 				.filter((ext) => ext !== ''),
@@ -1058,6 +1070,62 @@
 
 					<hr class=" border-gray-100 dark:border-gray-850 my-2" />
 
+					<div class="mb-2.5 flex w-full justify-between">
+						<div class="self-center text-xs font-medium">{$i18n.t('File Decryption')}</div>
+						<div class="flex items-center relative">
+							<Switch bind:state={RAGConfig.ENABLE_FILE_DECRYPTION} />
+						</div>
+					</div>
+
+					{#if RAGConfig.ENABLE_FILE_DECRYPTION}
+						<div
+							class="space-y-2.5 pl-6 border-l-2 border-gray-100 dark:border-gray-800 ml-1"
+						>
+							<div class="flex w-full justify-between items-center">
+								<div class="self-center text-xs font-medium">
+									{$i18n.t('Decryption Endpoint URL')}
+								</div>
+								<input
+									class="flex-1 w-full text-sm bg-transparent outline-hidden text-right"
+									type="text"
+									placeholder={$i18n.t('Enter Azure Function Endpoint')}
+									bind:value={RAGConfig.FILE_DECRYPTION_ENDPOINT}
+									autocomplete="off"
+									required
+								/>
+							</div>
+
+							<div class="flex w-full justify-between items-center">
+								<div class="self-center text-xs font-medium">{$i18n.t('API Key')}</div>
+								<div class="max-w-[180px]">
+									<SensitiveInput
+										placeholder={$i18n.t('Enter API Key')}
+										bind:value={RAGConfig.FILE_DECRYPTION_API_KEY}
+										required
+									/>
+								</div>
+							</div>
+
+							<div class="flex w-full justify-between items-center">
+								<div class="self-center text-xs font-medium">{$i18n.t('Timeout (seconds)')}</div>
+								<input
+									class="w-auto text-sm bg-transparent outline-hidden text-right"
+									type="number"
+									placeholder="30"
+									bind:value={RAGConfig.FILE_DECRYPTION_TIMEOUT}
+									autocomplete="off"
+									min="1"
+								/>
+							</div>
+
+							{#if !RAGConfig.FILE_DECRYPTION_ENDPOINT || !RAGConfig.FILE_DECRYPTION_API_KEY}
+								<div class="text-xs text-red-500 text-right">
+									{$i18n.t('Endpoint URL and API Key are required when file decryption is enabled.')}
+								</div>
+							{/if}
+						</div>
+					{/if}
+
 					<div class="  mb-2.5 flex w-full justify-between">
 						<div class=" self-center text-xs font-medium">{$i18n.t('Allowed File Extensions')}</div>
 						<div class="flex items-center relative">
diff --git a/src/lib/components/chat/MessageInput.svelte b/src/lib/components/chat/MessageInput.svelte
index 147f84220a..107053a50b 100644
--- a/src/lib/components/chat/MessageInput.svelte
+++ b/src/lib/components/chat/MessageInput.svelte
@@ -533,7 +533,15 @@
 		files = [...files, fileItem];
 
 		if (!$temporaryChatEnabled) {
+			let loadingToastId = null;
+
 			try {
+				// Show loading toast for decryption if enabled in config
+				if ($config?.file?.decryption_enabled ?? false) {
+					loadingToastId = toast.loading($i18n.t('Decrypting and uploading file...'));
+				} else {
+					loadingToastId = toast.loading($i18n.t('Uploading file...'));
+				}
 				// If the file is an audio file, provide the language for STT.
 				let metadata = null;
 				if (
@@ -568,11 +576,22 @@
 					fileItem.url = `${WEBUI_API_BASE_URL}/files/${uploadedFile.id}`;
 
 					files = files;
+					toast.success($i18n.t('File uploaded successfully.'), { id: loadingToastId });
 				} else {
 					files = files.filter((item) => item?.itemId !== tempItemId);
+					toast.dismiss(loadingToastId);
 				}
 			} catch (e) {
-				toast.error(`${e}`);
+				toast.dismiss(loadingToastId);
+				const errMsg = typeof e === 'string' ? e : (e?.message || `${e}`);
+				if (
+					errMsg.toLowerCase().includes('decryption') ||
+					errMsg.toLowerCase().includes('azure function error')
+				) {
+					toast.error($i18n.t('File decryption failed: {{error}}', { error: errMsg }));
+				} else {
+					toast.error(`${errMsg}`);
+				}
 				files = files.filter((item) => item?.itemId !== tempItemId);
 			}
 		} else {